Regenerative medicine series - Blog 3 of 3
- Tom Barton

- Sep 14
- 4 min read
Updated: Sep 15
Blog 3: The Power of Combination Treatments in Regenerative Medicine
Recap: Injectables in Regeneration
In the first two blogs of this three-part series, we explored how ageing affects the body and the injectable options available to address collagen loss, volume changes, and reduced skin quality. Treatments such as Jalupro, polynucleotides, Sculptra, PRP, exosomes, anti-wrinkle injections, and fillers each play an important role in restoring and revitalising the skin.
Now, in our final instalment, we focus on the role of energy-based devices and how combining these with injectables and supportive treatments can achieve truly transformative, long-lasting results.
Energy-Based Devices: How They Work and What They Do
At TT Medical Clinic, we use a carefully selected portfolio of energy-based technologies, chosen for their proven ability to stimulate collagen, resurface skin, and improve overall tissue health.
3D TriMax Radiofrequency Microneedling
This treatment uses ultrafine needles to create controlled microchannels in the skin while simultaneously delivering radiofrequency energy deep into the dermis. The dual action stimulates natural wound-healing and collagen production, leading to firmer, smoother, and tighter skin.
Benefits: Skin tightening, improved laxity, reduced lines, better texture, and long-term collagen stimulation.
Particularly effective for: lower face laxity, jowls, fine lines, acne scarring, and enlarged pores.
3D Vjuve CO₂ Fractional Laser
This advanced fractional laser precisely removes tiny columns of damaged skin, allowing healthy tissue to regenerate in its place. The process triggers strong collagen remodelling while resurfacing the skin’s outer layer.
Benefits: Reduced fine lines and wrinkles, improved skin texture, reduced pigmentation, scar softening, and an overall smoother, more radiant complexion.
Particularly effective for: sun damage, stubborn lines, textural concerns, and skin showing more advanced signs of ageing.
Dermalux Flex LED Light Therapy
Dermalux uses clinically proven wavelengths of light to stimulate cell activity, reduce inflammation, and enhance healing. Unlike laser or microneedling, LED is non-invasive, painless, and has no downtime, making it an excellent add-on to more intensive procedures.
Benefits: Calms redness, speeds recovery, boosts collagen, and improves overall skin health.
Particularly effective for: post-treatment recovery, sensitive skin, acne, rosacea, and maintaining results over time.
The Power of Combination Approaches
While energy-based treatments deliver excellent results on their own, the most impressive, natural-looking outcomes often come from layering injectables with device-based therapies. Ageing is multifactorial, so addressing just one layer is rarely enough.
Injectables + Radiofrequency Microneedling
Collagen-stimulating injectables such as Jalupro or Sculptra provide the “building blocks,” while RF microneedling enhances the repair response and tightens tissue. Together, they work to firm and strengthen skin from both the inside and outside.
Injectables + CO₂ Laser
For clients with more advanced ageing, combining biostimulators with fractional CO₂ resurfacing offers both structural rebuilding and surface refinement. The result: tighter, smoother, brighter skin with fewer lines and improved texture.
LED + Medical-Grade Masks
Adding LED light therapy after injectables or energy treatments enhances healing, reduces downtime, and amplifies collagen production. Paired with clinical-grade soothing masks, it creates a full-circle treatment experience.
PRP or Exosomes with Microneedling
Delivered directly into the skin, these regenerative options improve dermal quality, texture, and vitality, especially for delicate areas such as the under-eyes.
Preparation and Maintenance: Setting the Skin Up for Success
Energy treatments rely on the body’s ability to repair and build collagen. For this reason, pre-treatment preparation is essential.
Hydrated, healthy skin responds best:
The CO₂ laser in particular works significantly better on hydrated skin, as it targets water as its primary chromophore (the part of a molecule that absorbs light energy). If there is insufficient water in the skin, the laser cannot penetrate effectively, reducing results.
In radiofrequency microneedling, dehydrated skin creates high impedance (resistance to energy transfer). While the 3D TriMax can compensate by automatically increasing RF delivery, this can make the treatment more uncomfortable and limit the ultimate results.
Medical-grade skincare is vital to prepare the skin—boosting hydration, improving barrier function, and priming it for regeneration.
Nutritional support such as Jalupro injections and Skinade collagen drinks provides the body with the amino acids, peptides, and nutrients needed to maximise the collagen response triggered by energy treatments.
By combining preparation, in-clinic treatment, and at-home care, we ensure your skin is equipped to heal efficiently and deliver the best possible results.
Concerns Best Addressed with Combination Approaches
Skin laxity and sagging → RF microneedling + Sculptra or Jalupro Super Hydro
Wrinkles and textural changes → CO₂ laser + Jalupro or polynucleotides
Under-eye crepiness or hollowing → Jalupro Young Eye or polynucleotides + LED light
Pigmentation and sun damage → CO₂ laser + AlumierMD skincare
Overall skin vitality → PRP or exosomes microneedled + LED + medical-grade skincare
👉 This list is not exhaustive. Every individual may benefit from different combinations of treatments, and the best outcomes are achieved by tailoring treatment plans to optimise each person’s unique response.
Closing Thoughts: The Future of Regenerative Aesthetics
This three-part blog series has explored the science of ageing, the power of regenerative injectables, and the transformational role of energy-based devices.
The future of aesthetic medicine lies not in quick fixes but in holistic, regenerative approaches that restore the body’s natural ability to repair itself. By combining injectables, energy devices, supportive therapies such as LED and medical masks, and daily medical-grade skincare, we can create tailored plans that deliver subtle, natural, and long-lasting results.
At TT Medical Clinic, our philosophy is simple: work with your body, not against it. With regenerative medicine, we can help you look refreshed, revitalised, and confident—while still looking like you.




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